Learn about early diabetes symptoms, diabetic diet information, diabetes care, type 1 diabetes, insulin resistance and type 2 diabetes. Read the latest medical research on diabetes.
Scientists claim that overeating is not the primary cause of obesity
A perspective article challenges the 'energy balance model,' which says weight gain occurs because individuals consume more energy than they expend. According to the authors, 'conceptualizing obesity as a disorder of energy balance restates a principle of physics without considering the biological mechanisms underlying weight gain.' The authors argue for the 'carbohydrate insulin model,' which explains obesity as a metabolic disorder driven by what we eat, rather than how much. *Public health messaging exhorting people to eat less and exercise more has failed to stem rising rates of obesity and obesity-related diseases. *The energy balance model, which says weight gain is caused by consuming more energy than we expend, "restates a principle of physics without considering the biological mechanisms driving weight gain." *The carbohydrate-insulin model makes a bold claim: overeating doesn't cause obesity; the process of getting fat causes overeating. *The current obesity epidemic is due, in part, to hormonal responses to changes in food quality: in particular, high-glycemic load foods, which fundamentally change metabolism. *Focusing on what we eat rather than how much we eat is a better strategy for weight management.
New method enables 3D microscopy of human organs
Researchers have now demonstrated a method by which specific cell types in human organs can be studied with micrometer precision. The method can be used to reveal previously unrecognized alterations in the pancreas, but it can also be used to study other human organs and diseases.
Researchers observed association between standing and insulin sensitivity – standing more may help prevent chronic diseases
Insulin is a key hormone in energy metabolism and blood sugar regulation. Normal insulin function in the body may be disturbed by e.g. overweight, leading to decreased insulin sensitivity and increased risk of developing type 2 diabetes and cardiovascular diseases. Researchers have noticed that standing is associated with better insulin sensitivity. Increasing the daily standing time may therefore help prevent chronic diseases.
Mothers’ diabetes may induce premature aging of neural tissue leading to birth defects
About 300,000 to 400,000 fetuses per year from mothers with diabetes develop neural tube defects -- when the tissue that eventually forms the brain and spinal cord fails to form properly -- which can lead to miscarriage or profound disability. Now using studies in mice, researchers have identified the mechanism behind these structural birth defects, which they say is due to the neural tissue aging prematurely, halting its growth before it has made enough cells to finish forming the neural tube.
Discovery about cells' 'batteries' boosts battle against many diseases
A top exercise researcher reveals how our bodies ensure the proper functioning of the powerhouses of our cells. The findings could open the door to better treatments for many common diseases, including Alzheimer's and diabetes.